SLIM project in the "Volkskrant"

SLIM publications The 'SLIM' consortium has published some of it's relevant findings in four recent scientific publications (see references below). During the project, data was collected from hundreds of chemicals in two specific databases. One contained data relating to toxicity effects on


Check out our latest publications: Poland M, Ten Klooster JP, Wang Z, Pieters R, Boekschoten M, Witkamp R, Meijerink J. Docosahexaenoyl serotonin, an endogenously formed n-3 fatty acid-serotonin conjugate has anti-inflammatory properties by attenuating IL-23-IL-17 signaling in macrophages. Biochim

Barriers and drivers of regulatory acceptance and use of 3R methods

Marie-Jean Schiffelers, PhD candidate at the Utrecht University School of Governance (USBO) distilled the most important drivers and barriers that act upon regulatory acceptance of 3R methods. The conclusions have been summarized in a workshop report, published as an article in Regulatory Toxicology and Pharmacology.

Whooping cough vaccine safety

Check out our new publication on a novel alternatives-to-animals method to detect residues of active pertussis toxin (causing Whooping cough) in anti-whooping cough vaccine. Identification of biomarkers to detect residual pertussis toxin using microarray analysis of dendritic cells. Vaessen SF,

Inaugural speech / Openbare Les

Dr. Raymond Pieters and Dr. Cyrille Krul held their inaugural speech already some time ago. On March 6th 2009, over 200 people listened to their objectives, visions and opinions on the topic 'Innovative Testing'. Now, almost five years later many of the objectives have been met, but many have